How common is fatal or irreversible brain damage from hypoglycemia?

I'd like some relatively educated answers – don't answer if you'll post bullshit. I ask this question because someone I know took a 0.25 mg (1/2 tablet) of glibenclamide and went into a kind of coma. This shocked me because the medication was prescribed since he has Type 2 diabetes – I mean how on earth can a 1/2 tablet cause that kind of damage???
For the record, the tablet was Daonil.

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