Prevention of Diabetic Nephropathy
Diabetes is one of the most fatal health conditions around the world. There are a lot of types of this disease and they always run the risk of complications with other diseases. A good example to this is diabetic nephropathy, which is a failure or injury on the kidneys. It is also a common cause of a more serious disease, renal disease that is on the end-stage. It is also the condition that patients for chronic dialysis care have. In fact, 25 up to 40 percent of diabetes patients are suffering from this. The good thing is that prevention of diabetic nephropathy is possible.
Glycemic Control as Prevention of Diabetic Nephropathy
A known symptom of diabetic nephropathy is the presence of microalbuminuria, which basically represents generalized endothelial injury or renal injury. This also signifies cardiovascular risk on the person. Thus, by preventing microalbuminuria, the prevention of diabetic nephropathy is assured as well as any possibly of disease in the cardiovascular system. Hence, in diabetes, the appearance or presence of microalbuminuria is used as an important indicator of effective treatment intervention.
This can be done with the use of hypoglycemic drugs like thiazolidinediones (TZDs). Rosiglitazone and pioglitazone are good examples and are now commonly used in treating types 1 ad 2 diabetes. Studies showed that a percent decrease in A1C or hemoglobin A1c, micro- or macroalbuminuria incidence rate also decreases by 37 percent. The same is noticed with retinal complications.
Blood pressure control prevention of diabetic nephropathy
Studies have shown that the type of diabetes a person has can help detect the prevention of diabetic nephropathy. For example, the Eurodiab Controlled Trial of Lisinopril in Insulin Dependent Diabetes or EUCLID studies showed that type 1 diabetes patients have less chances of decreasing the incidence rate of microalbuminuria by lowering blood pressure while type 2 patients can. The same result is also validated by the trials of Appropriate Blood Pressure Control in Diabetes or ABCD.
Prevention of Diabetic Nephropathy in patients with microalbuminuria or its progression
Diabetic patients who have microalbuminuria can still prevent the progression of renal disease and diabetic nephropathy by inhibiting from ACE. Among the medications that the patients received are Ramipril, which noticeably reduced proteinuria progression rate and Irbesartan that protects type 2 diabetes patients from the progression of renal disease.
In summary, it clearly shows that diabetes patients can still prevent themselves from the progression of their condition to more complicated diseases with the help of modern medications. But the better choice is natural prevention of these diseases with the help of healthy lifestyle that includes indulging in balanced diet, exercise, and rest. Any kind of sickness can actually be avoided with all these natural ways, even diabetic nephropathy. But there are some things that can actually affect the health of a person, including the genes or if the sickness is hereditary. Diabetes, for one, is actually a disease that can be born with if one or both parents have it in them or in their families.