For those that have epilepsy, how difficult is taking your prescribed medication?

My wife has a difficult time keeping on hers She says she feels stiff after taking what should be her regular medicine routine. Anyone have this issue?
Yes, I guess that would help. She was prescribed with Dilantin from her teen years until a few years after we met when she was around 34. She's now 36. Then she was put on Lamictal, but thats expensive and with no insurance to help pay for it, she eventually went on Zonisamide(at least I think that is what it is called. ) From what I can tell she's been on and off since a teenager.