Question: I take 200 mg Celebrex every day for arthritis. My RN friend says she takes Mobic 15 mg and it is the only arthritis medicine her hospital prescribes since it is safer and works better than Celebrex. I want to know why it is safer and what, if any, are the side effects?
Answer: About celebrex: It is true that it is slightly better for the stomach (GI tract in general) and it does not have the detrimental side effects (increased cardiovascular morbidity and mortality) that vioxx and bextra had.
Mobic is a less specific COX-2 inhibitor and has never been shown to be any better than celebrex.
As mobic is not generic it is as expensive as celebrex.
If you are looking for a cheaper alternative to celebrex, I would recommend Etodolac as it is generic and overall better tolerated than ibuprofen or naprosyn.
From a personal standpoint: my mother tolerated celebrex ok but had severe stomach problems with mobic. As always YMMV.
Disclaimer: I am not a paid consultant for any of these companies and have no direct financial interest in them.